fMRI Discussion Group 06/12/09
Date: 06/12/2009, 01:00 PM – 02:00 PM
Location: Bldg 10 Rm 4N230
Presentations
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Reducing susceptibility artifacts in FMRI using multi-echo EPI with dynamic B0 and R2* correction (Staff scientist job talk)
(Souheil Inati, PhD,
Center for Brain Imaging, New York University)
The differences in the magnetic susceptibilities of tissue, bone, and air lead to variations in the static magnetic field (B0) and increases in the signal decay rate (R2*). The resulting image artifacts present one of the biggest technical challenges to high field FMRI. We have recently developed a set of data acquisition and image reconstruction tools to address this problem, and have demonstrated their effectiveness in several FMRI studies at 3T. The method combines a multi-echo gradient echo EPI pulse sequence with a non-linear algorithm to simultaneously estimate images of the spin density, B0, and R2* at each time point in the FMRI scan. Our method removes nearly all of the geometric distortions, recovers a substantial portion of the signal lost in standard single-shot EPI with conventional Fourier image reconstruction, and is robust to subject motion.
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